CBD % and MG's

What Do the Different CBD%s and the Number of CBDmgs in a CBD Product Actually Stand For?

When we talk about the percentage of CBD, the figure refers to the all-important strength of CBD that are in all our different CBD Oils, Softgels and Cosmetics. The percentage (%) strength of CBD always stays constant whether it is in 10ml, 20ml, 30ml, 50ml or any size bottle or jar, but the milligrams (mgs) of CBD has to increase as the bottle becomes larger in order to maintain the CBD% strength in the increased volume of the product. If you come across a CBD product that does not give you the CBD% then you would be wise to leave this product well alone. For example: If you wish to buy a CBD4% Oil you would need to have 400CBDmgs in a 10ml bottle, 800CBDmgs in a 20ml bottle, 1200CBDmgs in 30ml bottle, 2000CBDmgs in a 50ml bottle and so on.   

If you take an average daily dose of 3-4 drops, three times a day, that would mean consuming approximately 18-24mgs of CBD (based on our 4%CBD Oil). To give you some idea of the safety limitations, 160mg per day is seen as a recommended maximum amount for use, as a supplement.

This is why we recommend starting with our 4% CBD Oil, as this represents a middle-ground between the stronger and weaker concentrations. Even at four drops, three times a day, you would still only be consuming a maximum of 24mg of CBD. Don’t underestimate this therapeutic compound though—in some cases, this may be enough.

It is important to stress that everyone’s circumstances, and therefore dosage, will be different. Give yourself 2-3 weeks on a regular dosage to see how you feel before increasing or decreasing the amount of CBD, as necessary.

To help you calculate the amount (mg) of CBD being consumed, you can use the following as a guide:

2.5% CBD Oil: 1.25mg CBD per drop

4% CBD Oil: 2mg CBD per drop

5% CBD Oil: 2.5mg CBD per drop

10% CBD Oil: 5mg CBD per drop

20% CBD Oil: 10mg CBD per drop

30% CBD Oil: 15mg CBD per drop

Comparing The CBD Medical Group to other brands

Once you have an idea of the dosage you want to start with, or how you plan to increase your intake of CBD, the next most common query is, “how do our recommendations compare to other brands?”.

In truth, it is a nearly impossible question to answer. Not only does the amount of CBD needed to be impactful vary from person to person, but you also need to factor in the extraction method a company uses, their production techniques, and the purity of the final product. All of these attributes play a part in the efficacy of CBD, and therefore affect how much should be consumed.

While we cannot answer for other brands, we can highlight what you should take into consideration when selecting our golden CBD Oil and other CBD products in our range. State-of-the-art equipment and highly specialised CO extraction technology, alongside an expert team, ensure a safe and seamless production process from seed to bottle. The result is an oil that contains unadulterated CBD, while benefiting from the Entourage Effect (Full Spectrum) thanks to our process maintaining the benefits of all the natural terpenes in the Hemp Plant.

Dosage can also vary depending on the type of product

If keeping track of how many drops you've consumed proves difficult, don’t worry—that is why we also have a range of CBD Softgel Capsules. Each softgel capsule comes filled with a predetermined amount of CBD:

4% CBD Softgel Capsules: 6.4mg per capsule

10% CBD Softgel Capsules: 16mg per capsule

Again, the right dosage will depend on your circumstances, but taking one capsule three times a day is an excellent place to start.

A Conclusion on CBD Dosing

We have covered a lot of ground, and although dosage may seem like a daunting subject at first, the main takeaway would be: listen to your body. By using the recommendations above as a starting point, you can decide whether to increase or decrease the concentration of the CBD% based on how it makes you feel. As always, the key is to choose a reputable and trustworthy producer.

Can You Build Up A Tolerance To CBD?

Most people taking CBD are told that taking a regular, repeated dose is the key to getting the right results. But could taking CBD so regularly cause people to build up a tolerance and therefore constantly require a stronger dose? In this article, we take a closer look at whether it's possible to build up a tolerance to CBD.

Understanding Cannabinoid Tolerance

It is possible to build up a tolerance to some Cannabinoids, like THC. THC is the main psychotropic compound in Cannabis and delivers its effects by binding to CB1 receptors. These receptors work like little locks that are designed to be opened by Endocannabinoids like Anandamide and 2-AG, but some plant-derived Cannabinoids with a similar structure (like THC) can also bind directly to them.

When THC binds to these receptors, it can mimic endocannabinoids and cause the Endocannabinoid System to down-regulate in order to avoid becoming overactive. The ECS down-regulates by producing fewer endocannabinoids and fewer Endocannabinoid Receptors.

 As a result, people who regularly consume these Cannabinoids may find that they need increasingly larger doses in order to feel the same effects. This can also affect the Endocannabinoid System’s ability to learn and adapt to factors like stress as it has become over-dependent on THC.

What about CBD? Can it cause Tolerance?

No, CBD is very different from other Cannabinoids, and we’re still a fair way away from completely understanding this compound and its actions throughout the body. What we do know, however, is that it doesn’t bind to Cannabinoid receptors in the same way as THC. Instead, it acts via numerous other chemical pathways. Some resources suggest that CBD can activate over 60 different molecular pathways in the body.

 So far, studies indicate that CBD can affect serotonin receptors, vanilloid receptors, GABA receptors, gamma receptors, and more. Other studies show that CBD can inhibit a process known as reuptake, and thereby temporarily increase the amount of certain chemicals in the brain, such as serotonin and anandamide.

 While CBD doesn’t bind to endocannabinoid receptors, it can still interact with them indirectly. For example, studies have shown that it can work as an inverse agonist of CB1 receptors. Nonetheless, there is no current research claiming that CBD causes users to develop tolerance. Instead, it’s widely regarded as a safe, non-toxic compound that’s very well-tolerated. 

What is Reverse Tolerance?

In fact, some research suggests that CBD may cause reverse tolerance. Unlike THC, which occupies the role of endocannabinoids and can down-regulate the Endocannabinoid System, CBD can increase endocannabinoid levels (e.g. by inhibiting reuptake). Hence, over time, users may find that they need lower doses of CBD to get the same results. Though this is currently just a theory.

Unfortunately, our understanding of CBD and the endocannabinoid system is far from complete. There is still a lot more research needed before we can begin making concrete statements about CBD and how it works inside the body. However, current research shows that CBD doesn’t cause tolerance like other Cannabinoids might.

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